Introduction Secondary mitral regurgitation is a frequent consequence of ischemic cardiomyopathy and adverse left ventricular remodeling. Progressive mitral regurgitation increases left ventricular volume overload, worsens heart failure symptoms, and contributes to recurrent hospitalizations. Patients with prior coronary artery bypass grafting (CABG), advanced left ventricular dysfunction, chronic kidney disease, and multiple comorbidities often carry prohibitive surgical risk, making transcatheter edge-to-edge repair (MitraClip) an attractive therapeutic option. Case Presentation A 75-year-old male, known case of coronary artery disease status post CABG, hypertension, type 2 diabetes mellitus, hypothyroidism, chronic kidney disease, and ischemic cardiomyopathy, presented with worsening shortness of breath corresponding to NYHA Class IV functional status. He had experienced multiple recent admissions for decompensated heart failure. Prior to the current hospitalization, he ha...