50M with ESRD and Neck pain and stifness

Thanks to Authors : 
Dr. NIKITHA PULIPETA
Dr. SUPRAJA KANCHI


LEARNER REPORT
"This is an online E log book to discuss our patient's de-identified health data shared after taking his/her/guardian's signed informed consent. Here we discuss our individual patient's problems through series of inputs from available global online community of experts with an aim to solve those patient's clinical problems with collective current best evidence based inputs. This E log book also reflects my patient-centered online learning portfolio and your valuable inputs on the comment box

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February 01, 2022
50Y/M FOLLOW UP CASE.

I HAVE BEEN GIVEN THIS CASE TO SOLVE IN AN ATTEMPT TO UNDERSTAND THE TOPIC OF ''PATIENT CLINICAL DATA ANALYSIS'' TO DEVELOP MY COMPETENCY IN READING AND COMPREHENDING CLINICAL DATA INCLUDING HISTORY,CLINICAL FINDINGS,INVESTIGATIONS AND COME UP WITH A DIAGNOSIS AND TREATMENT PLAN. ( DR. NIKITHA PULIPETA )


click here to review previous blog ( DR. SUPRAJA KANCHI )



A 50 year old male patient is on maintainance haemodialysis since 10 months.

HOPI: patient was apparently asymtomatic 4yrs back and then developed shortness of breath (on and off), pedal oedema (pitting type).Later diagnosed as chronic renal failure and underwent dialysis twice weekly for about 10 months.
6 years back he met with an accident. His right leg got fractured and it took nearly 1 year to heal for which he used few medication continuosly for 1 year.

PAST HISTORY: k/c/o HTN since 1 year.
Not a K/C/O of DM, thyroid disorders, TB

PERSONAL HISTORY:He follows a mixed diet. Appetite -Normal, Bladder movements-normal,
Bowel movements-constipation since few weeks. Sleep- decreased.consumes alcohol regularly(90ml ) and stoped consuming1 year back.
He is a farmer and stopped working since 1 year.

FAMILY HISTORY: No significant family history.
DRUG HISTORY: No known drug allegies and patient uses Nicardia 10 mg.

General examination : patient is conscious ,coherrent, co operative and well oriented to his surroundings.he is poorly built and nourished.no pallor ,no cyanosis, no icterus, no lymphadenopathy. bilateral pedal edema is seen and is of pitting type 

Vitals:. Temperature: afebrile. Pulse rate: 98 beats / min. Respiratory rate: 19cycles / min. Bp: 190/100. Spo2: 99 

Systemic examination: 

Cvs: bilaterally symmetric chest wall .no precordial bulge .no thrills and no murmurs.
S1& S2 heard.
Respiratory system: no dyspnoea, no wheeze

Position of trachea- central, no adventious sounds heard


CNS: patient is normal and concious .reflexs are normal.

CLINICAL IMAGES:








Investigations: 31/1/22
RFT: urea-157. Cr.10.2. UA-9.8

USG- Rt Grade 3 RPD
          Lt grade 2 RPD

2D ECHO- trivial TR+ /AR+, no MR.
Good LV systolic function.
Diastolic dysfunction (+)

ECG:

2/2/22:
LFT: 
T.b-0.9. D.B- 0.2. SGOT-17. SGPT-15. ALKP- 504. TP-5.6. ALB-3.6. A/G RATIO-1.80

RFT: U-178. CR-10.2. U A-9.0. CALCIUM-9.4. P-4.5. Na-140. K-4.7. Cl-102

S.iron 78
RBS- 70
CUE: ALB++. SUGARS-TRACE. RBC's, CRYSTALS, CASTS-NIL

HAEMOGRAM
HB-5.8. TLC-7400. LYMPHOCYTES -13
PCV-17.4. RBC COUNT-2.01. PLT-1.20.    
NORMOCYTIC NORMOCHROMIC ANEMIA WITH THROMBOCYTOPENIA.

PROVISIONAL DIAGNOSIS:
NSAID ASSOCIATED RENAL IMPAIRMENT.

TREATMENT: 
(1) TAB.LASIX 40MG PO/BD
(2) TAB.NICARDIA 10 MG PO/BD
(3)TAB.NODOSIS 500MG PO/BD
(4)TAB.OROFER -XT PO/OD
(5)TAB.SHELCAL-CT PO/OD
(6)INJ.ERYTHROPIEOTIN 4000IU S/C ONCE WEEKLY
(7) SALT AND FLUID RESTRICTION.

COURSE IN HOSPITAL:
Patient has intermittent fever high grade on & off and neck pain since 1 month and neck stiffness with restriction neck movements since 10 days. Xray C-spine was taken which shows no bony abnormalities conservative management was done to relieve the pain. But patient symptoms didn't subsided. Mri C spine with whole spine screening was done. Which shows 




MRI C spine provisional : Infection involving odontoid processand surrounding Collection in paravertbral region.



As the size is very small and too deep into the skin, 20mm extending to epidural space ,it is inaccessible to do USG neck guided aspiration of abcess. By team radiology.



SIMILAR CASE REPORT-

A 65–year–old man on regular hemodialysis for long–standing chronic renal failure sought treatment after 2 days of progressively worsening neck pain. The patient described a febrile illness in the days preceding his admission. Examination of his peripheral nervous system was normal other than that he exhibited Lhermitte's sign.4 Based on this history, spinal sepsis was suspected. Blood was drawn for culture and sensitivity and urgent magnetic resonance imaging (MRI) was arranged. Gram–positive cocci were detected in the blood, and empirical therapy with vancomycin, flucloxacillin, and rifampicin was started. MRI of the craniovertebral junction showed an epidural mass around the odontoid process causing cervicomedullary compression and an abnormal hypointensity in the area on the right side of C1 . Subsequently, the bacteremia was confirmed to be due to Staphylococcus aureus. Day 3 of admission, the patient developed signs of respiratory distress and carbon dioxide retention. His lower cranial nerve function remained normal, but he exhibited upper motor neuron signs in both lower extremities. This clinical picture suggested worsening cervical epidural compression, and an emergency decompression of the foramen magnum and a C1 laminectomy were performed. At surgery the bone of the first cervical vertebra (Fig. 1B) was found to be soft, and a small amount of epidural pus was obtained. Postoperatively, he was immobilized in a halo head–fixation device. Proteus mirabilis was cultured from both specimens. The patient was then administered gentamicin and ciprofloxacin. Long–term venous access was established, and his response to treatment was monitored by regular measurement of blood inflammatory indices.




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